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Drug Name
Trandate (Labetalol)
Drug Uses
This medication is used to treat severe high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
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Follow the directions for using this medicine provided by your doctor. Take this medicine with food or milk.
Drug Class and Mechanism
Trandate is a drug that is used for treating high blood pressure. It is related to carvedilol (Coreg). Nerves that are part of the adrenergic nervous system travel to most arteries where they release an adrenergic chemical norepinephrine. The norepinephrine attaches to receptors on the muscles of the arteries and causes the muscles to contract, narrowing the arteries, and increasing the blood pressure. Trandate blocks receptors of the adrenergic nervous system. When trandate attaches to and blocks the receptors, the arterial muscles relax, and the arteries expand, resulting in a fall in blood pressure. The FDA first approved Trandate in 1997.
Missed Dose
If the dose is interrupted, contact the doctor immediately to re-establish dosing.
Storage
Store the vials at room temperature between 36 and 86 degrees F (2 to 30 degrees C) and away from light. Do not freeze. After dilution in the correct IV fluids, this product is stable for 24 hours refrigerated or at room temperature. Discard any unused liquid.
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